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Defined Bioscience

Regenerative Medicine

Regenerative Medicine Using Human Pluripotent STEM Cells (iPSCs)

Regenerative medicine aims to restore or replace damaged tissues and organs using stem cell-based therapies. Human induced pluripotent stem cells (iPSCs) offer a renewable and ethically sourced platform for generating patient-specific cell types used in regenerative therapies. These applications span neurology, cardiology, ophthalmology, dermatology, and more.

iPSCs can differentiate into virtually any cell type in the body, making them a powerful tool for regenerative medicine. Their patient-specific nature reduces the risk of immune rejection, and their scalability allows for the production of clinically relevant quantities of therapeutic cells. iPSCs are especially valuable in developing allogeneic and autologous therapies for neurological damage, cardiac repair, diabetes, and corneal regeneration.

Key challenges in regenerative medicine using iPSCs include ensuring consistent and safe differentiation into desired cell types, scalability for clinical applications, and maintaining genomic stability over multiple passages. Additionally, the cost and complexity of traditional stem cell culture systems hinder widespread adoption.

Defined Bioscience offers chemically defined, animal-free media and supplements optimized for both the maintenance and differentiation of iPSCs. Our HiDef-B8 medium provides robust expansion conditions, while Ready-CEPT enhances cell survival and supports efficient cell recovery during routine passaging. Additional products like HiDef PBS/EDTA, HiDef-N2, and HiDef-ITS respectively support routine cell culture, neural differentiation, and serum reduction with clear application for regenerative therapies.

Defined Bioscience
HiDef-B8 400X Supplement - Defined Bioscience

HiDef® B8 Stem Cell Growth Medium

From $150.00
From $150.00 $150.00
Defined Bioscience
Ready-CEPT™ Cell Viability Enhancer - Defined Bioscience

Ready-CEPT™ Cell Viability Enhancer

From $150.00
From $150.00
Defined Bioscience
HiDef® PBS/EDTA Cell Dissociation Reagent - Defined Bioscience

HiDef® PBS/EDTA Cell Dissociation Reagent

From $18.00
From $18.00
Defined Bioscience
HiDef® N-2 Neural Medium Supplement - Defined Bioscience

HiDef® N-2 Neural Medium Supplement

From $100.00
From $100.00
Defined Bioscience
HiDef-ITS Cell Culture Supplement - Defined Bioscience

HiDef® ITS Cell Culture Supplement

From $70.00
From $70.00

Key Defined Bioscience Products for Regenerative Medicine

HiDef-B8: Complete, serum-free, defined media ideal for maintaining pluripotency and efficient differentiation.

Ready-CEPT: Optimized supplement promoting enhanced viability and function in various cell types.

HiDef PBS/EDTA: Defined phosphate-buffered saline solution for gentle cell dissociation.

HiDef N-2: Defined neural supplement to support robust neural differentiation.

HiDef-ITS: Defined insulin-transferrin-selenium supplement to enhance proliferation efficiency and cell viability.

Application Notes

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High-density pluripotent stem cell expansion in a single-use bioreactor using HiDef S8

High-density pluripotent stem cell expansion in a single-use bioreactor using HiDef S8

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Optimized Expansion, Cryopreservation, and Recovery of Clinical Grade, PluriBank iPSCs Using a Defined Reagent System Kit

Optimized Expansion, Cryopreservation, and Recovery of Clinical Grade, PluriBank iPSCs Using a Defined Reagent System Kit

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Comparative Analysis of 2D and 3D Differentiation Approaches for iPSC-Derived Neural Cells

Comparative Analysis of 2D and 3D Differentiation Approaches for iPSC-Derived Neural Cells

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Isolating Induced Pluripotent Stem Cells by Using the WOLF G2 to Sort Stemness-Related Surface Markers

Isolating Induced Pluripotent Stem Cells by Using the WOLF G2 to Sort Stemness-Related Surface Markers

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Contact and Collaboration Opportunities

Defined Bioscience actively engages with the scientific community to support disease modeling research. We encourage researchers to reach out to our technical experts for collaboration opportunities, protocol optimization, and troubleshooting assistance.

info@definedbioscience.com

By leveraging Defined Bioscience products, researchers can accelerate their disease modeling studies, enhance experimental reliability, and advance therapeutic discoveries.

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